Tkinter doesn't have widgets that look like switches like Labview or anything, but apparently most OS's can be counted on to have check boxes so that's a thing in Tkinter. Either I'm finally getting used to this or it's' pretty easy to find useful examples on how to define checkboxs and how to grey them out:
Basic man page. In the examples the author seems to like the grid manager, but pack works just fine: http://www.python-course.eu/tkinter_checkboxes.php
A reminder to use an IntVar to return the status of the checkbox: http://stackoverflow.com/questions/16285056/get-the-input-from-a-checkbox-in-python-tkinter
A compact man page with nice lists of parameters and methods, including disable. http://www.tutorialspoint.com/python/tk_checkbutton.htm
A similar page for buttons showing how you can use the same settings to grey them out too: http://www.tutorialspoint.com/python/tk_button.htm